Vivus’ Qsymia appears to cut diabetes risk in some patients
MOUNTAIN VIEW, Calif. — Patients taking a drug used for weight loss were able to reduce their chances of developing Type 2 diabetes, according to a new study.
According to data from a 475-patient study published in the journal Diabetes Care, Vivus’ Qsymia (phentermine and topiramate) reduced the annualized incidence rate of Type 2 diabetes by up to 78.7% in high-risk, overweight or obese patients with prediabetes or metabolic syndrome. Prediabetes is a condition in which a person has elevated blood sugar and a high risk of developing Type 2 diabetes.
"These data demonstrate that medically assisted weight loss is highly effective in preventing progression to diabetes in an at-risk population, and underscores the observation that 10% weight loss achieves beneficial effects on metabolism and risk factors in patients with prediabetes and metabolic syndrome," University of Alabama nutrition sciences department chairman and study lead author Timothy Garvey said.
Increased drug utilization can decrease Medicare spending, NASP speaker says
SAN ANTONIO — An increase of 1% in prescribed drug use decreases Medicare spending on other medical services by 5%, according to statements made Tuesday at a specialty pharmacy conference by a former chief of staff for the Obama administration.
Speaking at the National Association of Specialty Pharmacy’s Strategic Business Exchange in San Antonio, Nancy-Ann DeParle cited a Congressional Budget Office report that she said helped underscore the important role that specialty pharmacy plays in healthcare cost containment, adding that the conservative nature of the CBO and actuaries led her to believe the actual effect of increased drug utilization was a 10% decrease in spending on medical services. The address lasted 90 minutes and included questions from industry panelists and members of the audience. DeParle is president Barack Obama’s former White House chief of staff for policy.
"The impact of the changes associated with the [Patient Protection and Affordable Care Act] are far-reaching, particularly in the specialty pharmacy industry," NASP CEO and co-founder Gary Cohen said. "It is essential that we continue to engage our community to continue the dialogue around this important issue."
DeParle said much remained to be done to "tweak" the healthcare reform law and acknowledged the "disappointing" technical performance of the federal insurance marketplace, which was overwhelmed by users when it debuted at the beginning of the month. But, she said, the response by millions of people "leads me to be encouraged as to how many people will come in and buy the insurance."
NCPIE outlines steps to improve adherence among elderly, polychronic patients
WASHINGTON — Calling it a "looming threat," the National Council on Patient Information and Education released a 10-step plan to draw attention to the problem of poor medication adherence among elderly people with multiple chronic conditions.
The report, titled "Accelerating Progress in Prescription Medicine Adherence: The Adherence Action Agenda," found that poor adherence among patients with chronic and comorbid conditions is resulting in disease progression and complications, as well as increased uses of more expensive healthcare services like emergency room visits, hospitalizations, re-admissions and post-acute care. Caring for about 27% of Americans with multiple chronic conditions accounts for 66% of the country’s health expenditures and is a major source of Medicare spending. Patients with six or more chronic conditions accounted for about 14% of the Medicare population and cost $32,658 per patient, or three times the national average, the report found. As a result, the cost of treating them was more than $140 billion, out of $300 billion in Medicare spending overall. Forty-two percent of elderly people took five or more drugs in 2012, with the average number of drugs increasing from five at age 65 years to seven at age 85 years.
"Although the challenge of poor medication adherence has been discussed and debated extensively, what is lacking is the clear recognition that prescription medicine use and the rising prevalence of chronic and comorbid conditions are inextricably linked and together represent a major opportunity to address this health threat," NCPIE EVP Ray Bullman said. "This report is intended as a wakeup call that action is needed now to confront this combined threat, before the continuing upsurge of chronic conditions overwhelms the healthcare system."
The 10 steps that the NCPIE outlined were:
- Establish medicine adherence as a priority goal of all federal and state efforts designed to reduce the burden of multiple chronic conditions.
- Establish the role of the patient navigator within the care team to help patients with multiple chronic conditions navigate the healthcare system and take their prescription medicines as prescribed.
- Promote clinical management approaches that are tailored to the specific needs and circumstances of individuals with multiple chronic conditions.
- Incentivize the entire healthcare system to incorporate adherence education and medication support as part of routine care for MCC patients.
- Eliminate the barriers that impede the ability of patients with multiple chronic conditions to refill their prescription medicines.
- Reduce the cost-sharing barriers for patients by lowering or eliminating patient co-payments for prescription medicines used to treat the most common chronic diseases.
- Accelerate the adoption of new health information technologies that promote medication adherence.
- Establish medication adherence as a measure for the accreditation of healthcare professional educational programs.
- Address multiple chronic conditions and optimal medication management approaches in treatment guidelines.
- Stimulate rigorous research on treating people with multiple chronic conditions, including focused research on medication adherence to promote the safe and appropriate use of different medicines in this patient population.
The NCPIE includes the National Association of Chain Drug Stores, the National Community Pharmacists Association, Cardinal Health, McKesson Corp. and others.