Study: Soy supplementation ineffective versus relief of menopausal symptoms
MIAMI — Soy isoflavone tablets do not appear to be associated with a reduction in bone loss or menopausal symptoms in women within the first five years of menopause, according to a report in the Aug. 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
The beginning stages of menopause often are accompanied by rapid bone loss, hot flashes, vaginal dryness and sleep disturbances among other symptoms. "Estrogen therapy with or without progesterone prevents most of these changes. However, as a result of the Women’s Health Initiative findings suggesting that the overall risks outweigh the benefits, most menopausal women now decline estrogen therapy, increasingly seeking other alternatives," noted lead researcher Silvina Levis. "Soy-derived products have been proposed to provide comparable benefits to estrogen but without the risks."
Levis, who is associated with the Miami Veterans Affairs Healthcare System and Miller School of Medicine, University of Miami, conducted a randomized controlled trial from July 2004 to March 2009 to determine the effectiveness of soy isoflavone tablets in preventing bone loss and other menopausal symptoms. Study participants received a soy isoflavone dose equivalent to approximately two times the highest intake through food sources in a typical Asian diet to ensure they received an effective dose. Women 45 to 60 years of age, within five years of menopause and with a bone mineral density T score (bone density compared with what is normally expected in a healthy young adult of the same sex) of -2.0 or higher in the lumbar spine or total hip were eligible for the study.
A total of 248 women were eligible for the study; 126 were randomized to the group receiving placebo tablets and 122 were randomized to the soy isoflavone group, who received 200 mg of soy isoflavone tablets daily. During two years of follow-up, no significant differences were found between women in the soy isoflavone group and placebo group regarding changes in bone mineral density of the spine (-2% vs. -2.3%), the total hip (-1.2% vs. -1.4%) or the femoral neck (-2.2% vs. -2.1%).
Additionally, the number of menopausal symptoms was comparable between the two groups at baseline and the end of the study, except hot flashes. At the end of the study, 48.4% of women in the soy isoflavone group and 31.7% of women in the placebo group reported hot flashes. The authors also found that a higher number of women in the soy group reported constipation compared with women taking placebo (31.2% vs. 20.6%) but this was not statistically significant, the researchers noted.
"Because of concerns regarding the risk of estrogens, a need exists for alternative interventions that could provide the beneficial effects of estrogens in bone and menopausal symptoms without the adverse effects on breast and cardiovascular health," Levis wrote. However, "we found that our population of women in the first five years of menopause, on average, had low rates of bone loss and that 200 mg of soy isoflavone tablets taken once daily does not prevent bone loss or reduce bone turnover or menopausal symptoms."
The study was supported by a grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health. The authors noted that, "the main shortcoming of the study was that only 248 of an expected 306 participants were enrolled, and higher-than-expected dropout rates led to a final sample size substantially lower than that predicted." However, even with the smaller sample size, "given the virtually identical results in the two groups, it is difficult to imagine that the results would have differed substantially with additional participants or better retention," the authors concluded. "Overall it does not appear that soy supplementation will play an important role in osteoporosis prevention."
NYX Cosmetics develops ‘Jerseylicious’-inspired makeup palette
LOS ANGELES — Attention “Jerseylicious” fans! NYX Cosmetics has teamed up with the Style Network for a multiplatform sponsorship that includes the creation of a co-branded makeup palette inspired by the network’s series “Jerseylicious.”
The new Haute Jersey Leopard Couture gives “Jerseylicious” fans the chance to fashion their own signature smoky eye and sun-kissed faux tan glow. The partnership also includes exclusive short-form content to air on Style and online at NYXCosmetics.com. NYX will be integrated into a new episode of “Jerseylicious” premiering Sept.18 at 8 p.m. ET/PT on Style.
As part of the partnership, Style has created a custom-tailored interstitial that will begin airing in August offering tips for viewers on how the new NYX palette can have them looking like their favorite “Jerseylicious” stylist. Then on Sept. 18, the product will be featured on a new episode of the series with “Jerseylicious” stars Alexa, aka “The Glam Fairy,” and a bridal makeup artist in the tri-state area, helping makeup artist and friend Olivia create a variety of “how to” videos for NYX to post to their website.
Available in stores and online now, the new “Jerseylicious”-inspired product is co-branded with the show’s logo and tune-in information. Valued at $25, the makeup kit is draped with a leopard pattern in gold and black. It features 24 eye shadows in matte and shimmery hues, four bronzers, two micro Mega Shine lip glosses, two blushes and a double-sided mirror.
Target.com to offer the new Spa Sonic at-home spa set
NEW YORK — Launching online at Target.com on Aug. 1 is the new Spa Sonic Skin Care System face and body polisher.
The seven-piece, at-home spa set works to deeply cleanse the entire face and body. Its dermal penetrating action is designed to promote rapid absorption of skin care products and leaves skin toned and smooth.
Spa Sonic Skin Care System face and body polisher is a waterproof device, priced at $65, and can be used in the shower, bath or sink. It operates with four attachments (all included) — a small brush for the face, a large brush for the body, pumice for rough areas and a facial sponge for microdermabrasion and reduction of fine lines.