News

Study: Flu vaccines prevent hospitalizations in seniors, even when vaccine effectiveness is low

BY Michael Johnsen

ATLANTA — A new study from the Centers for Disease Control and Prevention found that flu vaccines prevent flu-associated hospitalizations in people 65 years and older, even during seasons when vaccine effectiveness is low, the agency stated Friday. The study reinforces CDC’s existing recommendation for annual vaccination of adults 65 years and older who are at high risk for serious flu-related complications and often most-impacted by serious flu disease each year, resulting in hospitalization or death.

The study, published in Clinical Infectious Diseases online on May 6, used statistical modeling to estimate flu-vaccine-prevented hospitalizations in adults aged 65 years and older for estimates of vaccine effectiveness against medically attended influenza illness, ranging from 10% to 70%. Researchers used CDC flu surveillance data collected during the 2011-12 and 2012-13 seasons. The 2011-12 season was considered to be a mild flu season, whereas the 2012-13 season was characterized as moderate to severe. Using data from these two seasons, researchers were able to determine the varying impact that flu vaccination had in terms of hospitalizations prevented. 

Findings showed that during the more severe 2012-13 flu season, a flu vaccine with 10% effectiveness (and 66% coverage) would avert about 13,000 hospitalizations, whereas a vaccine with 40% effectiveness would avert about 60,000 hospitalizations. In contrast, during the more mild 2011-12 season, a flu vaccine with the same two effectiveness estimates would avert about 2,000 and 11,000 hospitalizations, respectively.

CDC estimates for overall vaccine effectiveness against medically attended influenza illness (across all age groups) for 2011-12 are 47% and for 2012-13 are 52%. The estimates for people 65 and older are 43% for 2011-12 and 32% for 2012-13. Vaccine coverage among people 65 years and older during 2011-12 is estimated to be 65% and 66% during 2012-13.

In addition to estimating hospitalizations prevented by vaccination during these two seasons, the study’s authors also analyzed how many people would need to be vaccinated to prevent one hospitalization. For the 2012-13 season, 476 people would need to be vaccinated to prevent one hospitalization, assuming vaccine effectiveness was 40%; whereas, for the 2011-12 season, 2,457 people would need to be vaccinated to prevent one hospitalization.

Therefore, the study showed that flu vaccination provides a greater benefit against hospitalization during moderate to severe seasons compared with milder seasons, and the number of people who need to be vaccinated to prevent hospitalizations is lower during moderate to severe seasons than during milder seasons. The reason for this is that more people are hospitalized during more severe seasons.

Researchers have known for some time that flu vaccine effectiveness generally is lower in the elderly than in younger, healthy adults. However, this research is reassuring that even when flu vaccination is associated with lower vaccine effectiveness, it can still have a measurable and significant impact on preventing hospitalizations in adults 65 years and older, the CDC stated.

keyboard_arrow_downCOMMENTS

Leave a Reply

No comments found

TRENDING STORIES

News

DenTek launches ‘Go Floss Yourself’ campaign

BY Antoinette Alexander

MARYVILLE, Tenn. — Oral care company DenTek has announced the launch of its "Go Floss Yourself" campaign and contest, inspired by the idea to encourage people across the country to be bold enough to tell a co-worker, friend or loved one that they need to go floss.

"The situation where a co-worker or family member has a piece a food stuck in their teeth happens more often than not," said Rachel Scharfman, brand director of DenTek. "This campaign was put in place as a way to relieve people of these embarrassing moments, like when you get home from work and realize you have lunch stuck in your teeth."

As a way to encourage people to start the conversation about protecting their smile and flossing, DenTek has partnered with Brickfish to launch the campaign and contest with a montage of videos highlighting different situations where loved ones or family members are finding the courage to tell each other to "Go F themselves" on GoFlossYourself.com. By leveraging relatable situations, DenTek is aiming to start a conversation about flossing and positioning flossing as a solution to stop possible embarrassment by making light of the problem that everyone encounters.

To further encourage the conversation, DenTek will be hosting weekly contests tied to the campaign to get people flossing, with the grand prize being a trip to San Juan, Puerto Rico or $5,000 cash. To enter the contest, users can submit a video or photo of themselves flossing with DenTek Floss Picks on GoFlossYourself.com between May 12 and June 23 , then share their entries and encourage friends and family to "like" and share their entries. Once the contest ends, DenTek will choose the winners from the top 20 entries with the most "likes" and "shares."

keyboard_arrow_downCOMMENTS

Leave a Reply

No comments found

TRENDING STORIES

News

Valeant grants Actavis license to market generic Acanya Gel beginning July 1, 2018

BY Michael Johnsen

DUBLIN — Actavis on Monday announced that it has entered into an agreement with Valeant Pharmaceuticals International to settle all outstanding patent litigation related to Actavis’ generic version of Acanya (clindamycin phosphate and benzoyl peroxide) Gel, 1.2%/2.5%.  Acanya Gel is a lincosamide antibiotic and benzoyl peroxide indicated for the topical treatment of acne vulgaris.

Under the terms of the agreement, Valeant will grant Actavis a license to market its generic Acanya Gel beginning July 1, 2018 or earlier under certain circumstances. Other details of the settlement were not disclosed.

Launch of Actavis’ product is contingent upon Actavis receiving final approval from the Food and Drug Administration on its abbreviated new drug application for generic Acanya Gel. Based on available information, Actavis believes it may be a "first applicant" to file an ANDA for the generic version of Acanya Gel and, should its ANDA be approved, may be entitled to 180 days of generic market exclusivity.

For the 12 months ended Feb. 28, Acanya had total U.S. sales of approximately $121 million, according to IMS Health data.

 

 

keyboard_arrow_downCOMMENTS

Leave a Reply

No comments found

TRENDING STORIES