Study: Effient reduces cardiovascular risk among younger, heavier patient cohort
INDIANAPOLIS — A special group of patients who participated in a trial of a heart disease drug made by Daiichi Sankyo and Eli Lilly showed fewer heart attacks, strokes and deaths related to cardiovascular disease than patients taking a competing drug, according to an analysis of study results.
Researchers examined results from the "TRITON-TIMI 38" study of Effient (prasugrel), focusing on 10,804 patients who belonged to the "core clinical cohort," meaning patients who were younger than 75, weighed 132 lbs. or more and who had no prior history of stroke or transient ischemic attack, an episode in which a person has stroke-like symptoms for up to one or two hours; transient ischemic attacks are a warning sign of possible future strokes. The Food and Drug Administration approved Effient in 2009.
The analysis showed that among patients in the core clinical cohort, those taking Effient had a 26% reduction in their risk of heart attacks, cardiovascular death or stroke compared with those taking Plavix (clopidogrel), a drug in the same class made by Bristol-Myers Squibb and Sanofi.
Smarter Shopping mobile app brings resources, answers to fingertips
OMAHA, Neb. — A free mobile application launched by ConAgra Foods, in partnership with "Supermarket Guru" Phil Lempert, seeks to offer consumers smarter ways to shop.
The new Smarter Shopping iPhone app hosts the following features:
The Supermarket Guru’s "Tip of the Week;"
The latest news and food trends with Lempert’s weekly Food News Today webcast, plus recalls and food safety alerts;
Lempert’s Hits and Misses feature for reviews and product ratings of the newest products at the grocery store;
An organics guide, which guides shoppers on which organic products are worth the additional cost;
A produce guide that directs consumers to which produce is ripe, or in season, in their area;
A recipe database for quick and easy recipes that you can sort by occasion, lifestyle and more; and
A label translator helps demystify some of the most common ingredients on labels.
"Thanks to my partnership with ConAgra Foods, consumers can now get handheld access to my weekly grocery shopping tips, food trends, recall information and more with a free iPhone app," Lempert said. "The new iPhone app offers the great Supermarket Guru resources and tips and news you’ve come to know and love, in a convenient, on-the-go format."
Walmart encouraged by sales improvement, reaffirms commitment to EDLP
BENTONVILLE, Ark. — Despite the absence of top line growth at Walmart’s U.S. stores division, second-quarter earnings grew 12.4% to $1.09 and came in a penny ahead of analysts’ estimates, which was enough for the company to narrow and increase the range of its full-year profit forecast.
Full-year earnings per share now are expected to fall within the range of $4.41 to $4.51, which is a tighter window and a penny higher than the guidance of $4.35 to $4.50 provided back in February when fourth-quarter results were released. Total company sales for the second quarter increased 5.5% to $108.6 billion, aided by a $2.3 billion currency exchanged benefit, and profits increased 5.7% to $3.8 billion.
The company’s profit performance is noteworthy, given the ongoing difficulties with the U.S. stores division, where a 0.9% same-store sales decline was the ninth consecutive quarter of negative comp growth and came on top of a prior-year decline of 1.8%.
Wal-Mart Stores president and CEO Mike Duke said he was encouraged by the sales improvement in the United States, which increased sequentially each month within the quarter.
“In fact, this was the best quarterly performance since the third quarter of fiscal 2010,” Duke said. “We’re committed to delivering positive comp sales by widening the gap on price, and we have a specific plan to deliver [everyday low prices] to every customer.”
Also sounding an optimistic tone was Walmart U.S. president and CEO Bill Simon, who said he was encouraged by sales momentum from the second quarter.
“Our grocery and health-and-wellness business, representing two-thirds of our sales continued to deliver positive comps,” Simon said. “Our hardlines and apparel businesses are improving.”
Sales at the stores division increased 0.4% to nearly $64.9 billion, while operating profits grew 2.1% to nearly $5 billion, and Simon indicated that based on the start of August sales he was confident the company’s plans are working and will produce ongoing sales improvement.
However, expectations for same-store sales in the third quarter continue to envision a potential decline with the range of possibilities extending from a 1% decline to a 1% increase. Simon noted that this year’s third quarter ends on Oct. 28 and therefore could be negatively affected by last minute Halloween sales, which would fall in the fourth quarter.
Comps are expected to turn positive by the fourth quarter, according to Simon and other executives at the company, who contend the emphasis on EDLP on a broad assortment of merchandise will continue to gain traction.
“As you have heard from us before, we know that strengthening price leadership starts with being the low-cost provider,” Wal-Mart Stores CFO Charles Holley said. “As we continue to lower our costs, we will also be investing in price, helping our customers save money so they can live better. We will be relentless in widening the price gap, as Mike (Duke) says, to pass savings along to our customers around the world. We believe that EDLP will lead to top line growth as customer traffic improves.”
Walmart ended the second quarter with a total of 9,230 units worldwide, including 4,427 stores in the United States. The company now operates 2,933 supercenters and the number of discount stores has dwindled to 692 units as they continue to be converted to supercenters. There were 609 Sam’s Club, 183 Neighborhood Markets and 10 small format stores at the end of the second quarter.
A little more than half of Walmart’s store base, or 4,803 units, are now located outside of the U.S. in the following markets: Mexico (1,789); United Kingdom (536); Brazil (484); Japan (413); China (338); Canada (325); Chile (290); Costa Rica (183); Guatemala (177); El Salvador (78); Argentina (64); Nicaragua (62); Honduras (58) and India (6).
The international division grew sales by 16.2% to $30 billion and operating profits increased 8.9% to $1.4 billion.
The strongest performance was turned in by Walmart’s small division. Sam’s Club same-store sales increased 5%, at the high end of the company’s guidance range and marked the sixth consecutive quarter of sequential improvement. Sam’s total sales increased 9.5% to $13.6 billion and operating profits increased 15% to $492 million. Sam’s Club president and CEO Brian Cornell said he expects third-quarter comps to increase between 3% and 5%.