HEALTH

Lack of sleep may increase IFG risk, study finds

BY Allison Cerra

NEW YORK Lack of beauty sleep may up one’s risk of developing a condition that leads to diabetes and heart disease, a new study found.

Researchers from Warwick Medical School and the State University of New York at Buffalo examined six years of data from 1,455 participants in the Western New York Health Study, all of whom were between the ages of 35 and 79 years, and found that people who sleep less than six hours a night may be three times more likely to develop incident-impaired fasting glycaemia. IFG causes the body to be unable to regulate glucose as efficiently as it should.

Lead author at Warwick Medical School Dr. Saverio Stranges said: "We found that short sleep, less than six hours, was associated with a significant, threefold increased likelihood of developing IFG, compared [with] people who got an average of six to eight hours sleep a night. Previous studies have shown that short sleep duration results in a 28% increase in mean levels of the appetite stimulating hormone ghrelin so it can affect feeding behaviors. Other studies have also shown that a lack of sleep can decrease glucose tolerance and increases the production of cortisol, a hormone produced in response to stress."

 

Stranges added that, "more research is needed, but our study does suggest a very strong correlation between lack of sleep and Type 2 diabetes and heart disease."

 

The study was published in the journal Annals of Epidemiology.

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Decision Resources: Market for Alzheimer’s disease drugs will expand

BY Alaric DeArment

BURLINGTON, Mass. Biotech drugs for treating Alzheimer’s disease will more than triple the size of the market in several key countries over the next decade, according to a new report by industry research company Decision Resources.

The report showed that bapineuzumab, made by Johnson & Johnson and Pfizer, and Eli Lilly’s solanezumab will drive the market for Alzheimer’s drugs from 2009’s $4.3 billion to $13.3 billion in 2019 in the United States, Japan, the United Kingdom, Germany, France, Italy and Spain.

Whereas most current Alzheimer’s drugs are acetylcholinesterase inhibitors, or AChEIs, which treat the disease’s cognitive symptoms without modifying its course, the new drugs have the potential to slow the rate of neural degeneration and cognitive decline, according to the report. Still, sales of AChEIs will remain strong through the decade.

“Despite increased generic competition and the launch of more-expensive and potentially more-efficacious therapies, AChEI sales will be buoyed through 2019,” Decision Resources director Bethany Kiernan said. “This will be largely due to an overall market expansion driven by increases in the number of drug-treated patients but also, to a lesser extent, by the launch of new formulations of branded AChEIs.”

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NCPP: Preventative health services can save lives, money

BY Michael Johnsen

MINNEAPOLIS Preventative health services, such as daily aspirin use, tobacco-cessation screening and alcohol-abuse screening potentially can save 2 million lives and nearly $4 billion annually, according to a new paper produced by the National Commission on Prevention Priorities.

 

The paper, “Greater Use Of Preventative Services In U.S. Health Care Could Save Lives At Little Or No Cost,” was published in the September issue of Health Affairs. Its authors analyzed the estimated cost of adopting a package of 20 proven preventative services against the savings that could be generated. They also estimated how much in healthcare costs would have been saved in a given year if 90% of the population had used those services. For 2006, the year selected, the savings were estimated at $3.7 billion.

 

 

“By quantifying the many lives saved and high cost-effectiveness of clinical preventative services, our study shows that prevention has really gone the extra mile, meeting a standard rarely met by health treatments,” stated Robert Gould, president and CEO for the Partnership for Prevention, the organization that established the NCPP. “The new healthcare law appropriately makes these services available for most Americans at lower or no cost, but cost reductions alone won’t get us there. We now need health purchasers, insurers and providers to make every effort to improve their delivery and educate the public about these life-saving preventative services.”

 

 

Most of the savings came from three services: tobacco-cessation screening and assistance, discussing daily aspirin use, and alcohol screening with brief counseling. The authors determined that those three services plus colorectal cancer screening each would have contributed more than 100,000 years of life if 90% of the population had participated.

 

 

“People talk about the importance of prevention, and this study shows that a significant number of recommended clinical preventative services saves lives and sometimes saves money,” said Eduardo Sanchez, chair of NCPP.

 

 

The full paper is available on the Partnership for Prevention website, Prevent.org.

 

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