PHARMACY

Irish government takes blame for failure of Amgen facility

BY Drew Buono

CARRIGTWOHILL, Ireland The Irish government is now being blamed after the biotech company Amgen decided to not build a new facility in Carrigtwohill, which was valued at $1,412,700,000 and would have required 1,100 jobs, according to the Irish Post.

The company has been quieting rumors about the new facility since April, when it announced a two-year delay in building the site. Also, two of Amgen’s drugs, Epogen and Aranesp have come under target by Medicare, who is questioning the dosing requirements for the drugs.

79 employees will lose their job by December as a result of this move. The facility was originally planned to open in 2012.

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Synta and GSK enter into $1.1 billion deal

BY Drew Buono

LONDON and LEXINGTON, Mass. Synta Pharmaceuticals and GlaxoSmithKline have agreed on a collaboration for the joint development and commercialization of STA-4783, a new drug entering phase-three clinical development for the treatment of metastatic melanoma.

Under the terms of the agreement, the companies will share responsibility for the development and commercialization of the drug in the United States, with GlaxoSmithKline having exclusive rights outside of the United States.  Synta can earn up to $1.1 billion as a result of this agreement in development, upfront payments, stock purchases and milestone payments.

“This agreement confirms GSK’s growing status as a world leader in the development of new oncology medicines for use in the treatment, prevention and supportive care of cancer patients.  It further strengthens our late stage oncology pipeline, which currently includes ten phase-three programs, and also demonstrates our commitment to identifying compounds that have the potential to deliver real benefit to patients,” said Moncef Slaoui, chairman of research and development at GSK.  “The data we have seen from the phase-two trials conducted by Synta have given us confidence in the potential of STA-4783 as a novel means of treating metastatic melanoma, a disease for which there is high unmet medical need.”

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CMS updates Medicare Part D Web site

BY Drew Buono

WASHINGTON The Centers for Medicare and Medicaid Services has updated its Medicare Prescription Drug Plan Finder, so that senior citizens and other beneficiaries can begin to review 2008 Part D drug plans.

The finder offers beneficiaries a chance to compare drug plans and health plans, view premiums, formularies and availability of coverage in the gap.  CMS wanted to make the finder as easy as possible to use and provide as much information as possible so that beneficiaries are ready before the open enrollment begins on Nov. 15.

The finder is at www.medicare.gov.

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