GSK halts Simplirix trial
LONDON British drug maker GlaxoSmithKline has stopped a late-stage trial of a vaccine for genital herpes, citing disappointing results, GSK said Thursday.
The company said that while the vaccine Simplirix (herpes simplex vaccine) proved to be safe when administered to women as a prevention for genital herpes disease, it did not prevent infection. GSK had been conducting the phase 3 trial in 8,323 women ages 18 to 30 years in the United States and Canada under a partnership with the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.
“We would like to express our gratitude toward our partner, [the National Institute of Allergy and Infectious Diseases], for [its] proactive collaboration and substantial contribution in the program, and the volunteers for their participation in the study,” GSK VP and director for late clinical development Gary Dubin said.
Waiting period for Bristol-ZymoGenetics deal expires
NEW YORK The Hart-Scott-Rodino waiting period for Bristol-Myers Squibb’s acquisition of Seattle-based biotech company ZymoGenetics has expired, enabling Bristol’s acquisition to go through, the drug maker said Tuesday.
The drug maker announced the deal to acquire ZymoGenetics for $885 million, or $9.75 per share, earlier this month.
The buyout gives Bristol ownership of Recothrom, a drug used to control bleeding during surgical procedures; an investigative treatment for hepatitis C called pegylated-interferon lambda; and an investigative treatment for melanoma called interleukin-21, or IL-21.
Valeant, Biovail become one
MISSISSAUGA, Ontario The merger between Valeant Pharmaceuticals International and Biovail is complete, the two companies said Tuesday.
Shareholders of both companies have approved the merger, worth more than $3 billion, originally announced in June.
The combined company will take Valeant’s name.