HEALTH

Donnenfeld joins Advanced Vision Research

BY Michael Johnsen

WOBURN, Mass. Advanced Vision Research named Eric Donnenfeld to the post of chief medical officer.

“Donnenfeld is one of the pre-eminent ophthalmologists practicing today with a broad scope of experience and knowledge,” stated Leigh Reynolds, Advanced Vision COO. “He is a key thought leader who will play a critical role for Advanced Vision Research as we move forward with new product research and development,” he said.

Donnenfeld has been a leader in ophthalmology for more than 20 years, the eye-care company stated. He is on the editorial board of nine medical journals, and is one of the authors of the American Academy of Ophthalmology’s Refractive Surgery Basic Science Book. Donnenfeld graduated with honors at the top of his class at Dartmouth Medical School.  He was chief resident at Manhattan Eye Ear and Throat Hospital and he completed his Cornea and Refractive Fellowship at Wills Eye Hospital in Philadelphia.

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HEALTH

New study finds hormone deficiency may cause chronic diarrhea

BY Allison Cerra

NEW YORK A common type of chronic diarrhea may be caused by a hormone deficiency, according to new research published in the November issue of Clinical Gastroenterology and Hepatology.

Chronic idiopathic bile acid diarrhea occurs when an overload of bile acid reaches the colon and causes excess water to be secreted into the bowel. The researchers in the study found that a hormone, FGF19, which normally switches off bile acid production in the liver, does not function properly.

The researchers tested the amount of bile acid being produced in the livers of 17 patients diagnosed with bile acid diarrhea and 19 healthy controls. They did this by measuring the amount of a molecule called C4 in the blood, which indicates how much bile acid is being made. The results showed that the people with bile acid diarrhea were producing an average of nearly three times more bile acid than the controls, with 51 nanograms of C4 per mL of blood in the patient group, compared to 18 nanograms per mL in the control group.

“Bile acid diarrhea is a common condition, likely to affect more people than Crohn’s disease or ulcerative colitis, yet until now we did not understand exactly what causes it,” said lead study author Julian Walters, from the Division of Medicine at Imperial College London. “Our new findings mean that in the future doctors may be able to diagnose the condition by doing a quick and simple blood test.”

These results suggest that there is a significant link between bile acid production and decreased levels of FGF19 in people with bile acid diarrhea. The researchers say that, following this small study, further research is needed to see if these findings can be replicated.

 

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HEALTH

Report: PSE legislation proposal hits Jefferson County, Mo.

BY Michael Johnsen

HILLSBORO, Mo. It started with two municipalities in neighboring Franklin County, and now Jefferson County, located just outside St. Louis, similarly has proposed to require prescriptions for the common cough-cold remedy pseudoephedrine in an attempt to curb methamphetamine production, The St. Louis Post-Dispatch reported Tuesday.

County executives recently voted unanimously to require prescriptions for over-the-counter medications containing the decongestant pseudoephedrine in the first of three readings the bill must pass before it can become law. If passed, the legislation would become binding for nine of the county’s 32 pharmacies, County Executive Ed Kemp told the paper. The other pharmacies fall within unincorporated areas.

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