PHARMACY

Cialis appears effective on enlarged prostate problems

BY Alaric DeArment

NEW YORK Eli Lilly’s drug Cialis (tadalafil) can treat enlarged prostates, according to a study appearing in the October issue of The Journal of Urology.

The study comprised a placebo-controlled study of more than 1,000 men in 10 countries with benign prostatic hyperplasia and found that Cialis can relieve associated lower urinary tract symptoms. The researchers administered doses of 2.5 mg, 5 mg, 10 mg and 20 mg per day and found the 5 mg dose most effective.

Cialis has approval from the Food and Drug Administration to treat erectile dysfunction. It had sales of $423.8 million in 2007, according to Eli Lilly financial data.

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King’s $1.4 billion bid rejected by Alpharma

BY Alaric DeArment

NEW YORK King Pharmaceuticals would gain access to a transdermal patch to treat pain if it acquired Alpharma.

So far, however, Alpharma isn’t interested in King’s $1.4 billion cash offer to acquire the company and its NSAID patch Flector and the Kadian extended-release morphine product, saying in a written statement that King’s three bids for the company since July have undervalued the company.

“We are willing to entertain a proposal from you that we believe more appropriately values the company,” Alpharma chief executive officer Dean Mitchell wrote in a letter to King chief executive officer Brian Markison. “To that end, we remain open to discussions with you at a price that we believe reflects the inherent value of Alpharma.”

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LDL cholesterol levels linked to cancers in diabetics

BY Alaric DeArment

NEW YORK LDL cholesterol has been linked to higher risk of cancer in patients with Type 2 diabetes, according to a study.

The study, conducted by researchers in Hong Kong, examined 6,107 patients with diabetes, none of whom took statins to lower cholesterol. It found that patients with LDL cholesterol levels less than 2.8 millimoles per liter of blood had higher risk of cancers in the digestive, reproductive, lymphatic and circulatory systems. Meanwhile, patients with levels greater than 3.8 millimoles had more risk of oral, bone, skin, breast and connective tissue cancers.

The researchers published their study in the Canadian Medical Association Journal.

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