Avandia to be available only by mail order in November, FDA asserts
SILVER SPRING, Md. — A controversial GlaxoSmithKline drug for treating Type 2 diabetes no longer will be available through retail pharmacies as of Nov. 18, the Food and Drug Administration announced Wednesday.
Avandia (rosiglitazone) and such related drugs as Avandaryl (rosiglitazone and glimepiride) and Avandamet (rosiglitazone and metformin) will be available only by mail order from specially certified pharmacies and for certain patients, such as those already successfully treated with the drug and those who can’t control their blood sugar with other diabetes drugs and don’t want to use other drugs belonging to the same class as Avandia.
The drug has attracted controversy due to studies showing that it increases the risk of heart attacks in patients taking it. In September 2010, the FDA moved to restrict access to the drug as part of a risk evaluation and mitigation strategy.
Study finds 10% of cancer patients abandon oral anti-cancer medications
WASHINGTON — Despite the promise of oral drugs for treating cancer, high costs and the burden of taking multiple medications drive 10% of patients prescribed the drugs not to fill their initial prescriptions, according to a new study published in the Journal of Oncology Practice and the American Journal of Managed Care.
Healthcare research firm Avalere Health conducted the study, “Patient and Plan Characteristics Affecting Abandonment of Oral Oncolytic Prescriptions,” by examining pharmacy transaction data on 10,508 patients from between 2007 and 2009, and will present results of the study at the American Society of Clinical Oncology’s annual meeting next month.
The study found that high cost and having to take multiple prescriptions were the leading factors in 10% of patients abandoning their drugs. For example, claims with cost sharing of more than $500 were four times as likely to be abandoned as those with cost sharing of $100 or less.
“Our study shows that many cancer patients are abandoning the medicine they need,” Avalere Health VP Lauren Barnes said. “With 45.5% of Medicare patients in our sample facing cost sharing greater than $500 for their first anti-cancer drug, this is a Medicare quality issue of the first order.”
Higher rates of abandonment were found among Medicare patients and those with lower incomes. Patients with incomes less than $40,000 per year had an abandonment rate of 11%, compared with 10% for those making $40,000 to $75,000, and 9% for those making more than $75,000. Among Medicare patients, abandonment rates were 16%, compared with 9% of those with commercial insurance. In addition, patients with more than five drug claims for noncancer medicines in the previous month had an abandonment rate of 12%, compared with 9% with no claims.
MinuteClinic announces clinical collaboration with Inova
WOONSOCKET, R.I. — CVS Caremark’s MinuteClinic division has announced a clinical collaboration with northern Virginia healthcare provider Inova Health System to enhance healthcare services provided in communities throughout Arlington, Fairfax, Fauquier, Loudoun and Prince William counties.
Inova operates a network of hospitals, outpatient services and healthcare centers that includes Inova Alexandria, Inova Fairfax, Inova Fair Oaks, Inova Loudoun and Inova Mount Vernon hospitals, and Inova Fairfax Hospital for Children.
MinuteClinic has 14 in-store health clinics throughout northern Virginia.
"Inova has a long-standing record of clinical quality and is one of the mid-Atlantic’s premier health systems," stated Andrew Sussman, president of MinuteClinic, and SVP and associate medical officer for CVS Caremark. "Like MinuteClinic, it shares a commitment to expanding access to care for the millions of residents living in northern Virginia, and it has developed several leading initiatives with the region’s top corporations to improve the health of their employees. We think MinuteClinic can be a valuable addition to these programs that promote employee wellness and lower healthcare costs."
Under the agreement, Inova will ensure that there is a collaboration with MinuteClinic’s medical directors, many of whom include Inova-affiliated family physicians. In addition, MinuteClinic and Inova also will collaborate on patient education and disease management initiatives, and will inform patients of the services each offers. Inova will accept patients who need a level of care that is not provided at MinuteClinic. Signage at MinuteClinic locations will inform patients that each site has a clinical affiliation with Inova.
MinuteClinic and Inova will begin to work toward fully integrating their electronic medical record systems to streamline communication around all aspects of each individual’s care.