Amgen seeks regulatory approval for bone metastasis treatment
THOUSAND OAKS, Calif. Amgen has submitted a regulatory approval application to the Food and Drug Administration for a drug to prevent the spread of tumors to the bones in cancer patients, the biotech company said.
The Thousand Oaks, Calif.-based drug maker announced the submission of a biologics license application to the FDA for denosumab. The regulatory submission was based on data from nearly 6,900 patients in 18 clinical studies, including three phase 3 studies comparing the drug with Novartis’ Zometa (zoledronic acid).
The spread of tumors to bones, also known as bone metastasis, is a serious concern for many patients with advanced cancer. When it happens, the cancer cells can weaken and destroy the bone around a tumor, raising the risk of fractures, spinal cord compression or the need for radiation therapy or bone surgery. Bone metastases occur in more than 1.5 million cancer patients worldwide, most often in those with prostate, lung and breast cancers, exerting an economic burden of $12.6 billion a year on cancer patients in the United States alone. The drug targets a biological pathway believed to be central in cancer-related bone destruction, regardless of cancer type.
“We believe that denosumab will offer substantial benefit to cancer patients suffering from bony metastases,” Amgen EVP research and development Roger Perlmutter said. “Denosumab, administered monthly as a 120-mg dose subcutaneously, demonstrated consistently similar or greater efficacy in clinical trials when compared to zoledronic acid, offering the potential to improve on the current standard of care. One potential advantage of denosumab is that dose adjustments resulting from declining renal function are not necessary.”
Meijer to carry Jitterbug J cell phones
SAN DIEGO GreatCall is expanding its retail reach — supercenter chain Meijer will carry the mobile service company’s entire line of Jitterbug J cell phones.
Available now, Meijer stores across five states will carry all three Jitterbug J handsets: white, graphite and red.
“We know that Jitterbug customers are consumers who look for a more personalized wireless experience, so we are very pleased that Meijer stores are now carrying the Jitterbug J handsets,” said Ryan Jones, VP sales for GreatCall. “The key to our continued success and attracting the attention of leading retailers such as Meijer is due in large part to giving our customers the services that add value to their daily routine, improve their safety and well-being, and help them easily connect with friends and family.”
Walgreens expands Community Corner program to showcase women-owned businesses
DEERFIELD, Ill. Walgreens’ supplier diversity initiative is featuring products produced by women-owned businesses on Walgreens.com through the end of May in honor of National Women’s History Month.
Walgreens’ Community Corner program launched in February with recognition of African-American-owned businesses in honor of Black History Month. Walgreens plans to continue expansion of the initiative to feature products produced by businesses with Hispanic-American, Native-American, and Asian-American ownership at different points throughout the year.
Through the end of the month, the following products will be featured at 50 percent off the regular price at Walgreens.com/cc:
- W Brand Sensitive Skin Shave Cream by Chase Products
- Triderma MD Eczema Fast Healing Cream by Genuine Virgin Aloe
- Blue Magic Conditioning Hair Dress by Strickland and Co.
- Ampro Pro Styl Gel by Ampro
- Wrap, Snap & Go! Comfort Hair Rollers by Exceptional Products
- Releev 1 Day Cold Sore Symptom Treatment by Merix Pharmaceutical
- Fleet Enema Saline Laxative by CB Fleet Company
- OCuSOFT Lid Scrub Eyelid Cleanser Pre-Moistened Pads by OcuSoft
- NonyX Nail Gel for Clear, Healthy-looking Toenails by Xenna Corp.
- MG217 Medicated Tar Shampoo by Triton Consumer Products
- Boogie Wipes, Gentle Saline Nose Wipes for Stuffy Noses by Little Busy Bodies
- Paper Jam Construction Paper by Maybe It’s Time
In addition to promoting its diverse suppliers, Walgreens is further developing its relationships with community organizations such as the National Minority Supplier Development Council, the Women’s Business Enterprise National Council and the National Urban League to support economic growth in communities.
“Walgreens has long embraced diversity – not only in the people it employs, but also in the array of community-built brands it selects to meet the needs of its broad and diverse customer base,” said Gleatha Glispie, Walgreens director of supplier diversity. “Providing a platform such as Community Corner fosters an environment that enhances the development of a diverse group of entrepreneurs and empowers consumers to instantly influence economic growth in their communities. We look forward to further expansion of this initiative.”