PALM BEACH GARDENS, Fla. — As many as 97% of parents are confident they administered the correct dose of acetaminophen when using AccuDial Pharmaceutical's weight-based dosing label, according to research published earlier this year.
In 2011 Concentric Research conducted a two-phase label comprehension and dosing study on behalf of AccuDial Pharmaceutical. In phase one, 61 adult parents/caregivers with children below 18 years old participated. In phase two 565 adult parents/caregivers with children below 18 years old participated. Of those, 10% of the parents were in the lower literacy category based on the REALM literacy test that all participants were required to take prior to participating in the study.
The primary objective of the study was to evaluate the ability of parents with children below age 18 to understand the dosing instructions of AccuDial's Children's Acetaminophen product with a new rotating weight-based dosing label (dosing comprehension) and to demonstrate their understanding by measuring a dose (dosing behavior) when given various scenarios.
As part of the phase one study, 30 participants evaluated the AccuDial acetaminophen dosing chart, and 31 participants evaluated the five Age/Weight Range Dosing chart — the dosing chart that national brand and store brand manufacturers display on their product labels.
Parents that evaluated AccuDial scored significantly higher — between 84% and 93% — in their comprehension of the correct amount of medication to give a child. There was less comprehension associated with using the Age/Weight Ranging Dosing chart.
In situations where a child's age and weight match the dosing directions on the Age/Weight Ranging Dosing chart, the comprehension was 80.6%. However, when the child's age and weight did not match the age/weight range on the chart, dosing comprehensions was between 58% and 67%. Parents were less sure of how to dose when their children were heavier than indicated on the chart against the corresponding age range.
The phase two study was conducted in 10 cities across the United States. Comprehension results for AccuDial ranged between 84% and 97%, and were statistically comparable to the comprehension results in phase one. The dosing section in phase two produced slightly better results, as 97% of parents were confident they administered the correct amount of medication.
In phase one AccuDial included a calibrated dosing spoon, and the Age/Weight Comparator product used a calibrated dosing cup. Between phase one and phase two, AccuDial replaced the calibrated dosing spoon with an oral syringe (and a Push-In Bottle Adapter). The syringe proved easier to measure the correct amount of medication, was easier to administer the medication directly from the syringe and parents were concerned that the thick viscosity of acetaminophen caused between .5 mL and 1.5 mL to remain in a dosing cup or spoon.
Subsequently, AccuDial includes a Push-in Bottle Adapter and oral syringe with all acetaminophen products.